Posts by admin

Critical Non-Dilutive Resources for NE Life Science Companies

Smart life science entrepreneurs in Greater Boston will find and use the resources of the vast ecosystem that has developed for their benefit. While this is not only an opportunity for high value and low cost growth, it is also a bit of a litmus test for those seeking equity capital. Investors demand capital efficiency and greatly value scrappy entrepreneurs who proactively seek out non-dilutive resources.

Earlier this year, real estate firm Jones Lang LaSalle ranked Greater Boston as the number one life science supercluster in the United States. The report ranked clusters on reportable jobs, venture funding and grant dollars. The concentration of “top-notch universities, innovation centers, research hospitals, venture capital firms, [and] a strong labor force” was cited as a key driver of such growth metrics.
However, the report did not include the presence or impact of non-profit, quasi-governmental and trade organizations that provide the necessary critical mass of infrastructure to support entrepreneurial growth in a region. Such “ecosystem players” generate key benefits for early stage life science companies. These include not just affordable and flexible lab space (the focus of the report), but also:
• grant capital
• loan capital
• coaching & mentoring
• matchmaking for co-founders, boards and SABs
• business development forums and support
• regulatory pathway consulting
• fundraising pitch events
• community events that drive employment opportunities
• product showcase events
• prototyping and manufacturing support for MedTech
• education around product development, entrepreneurship and fundraising

The area’s largest effort, the billion dollar Massachusetts Life Science Center (MLSC) is an example of quasi-governmental economic development support efforts. MLSC, using its incredible network of industry veterans, provides key grant and loan funding for early stage companies in various forms. This often complements early stage equity raises and provides substantial additional product development runway for early stage companies. Susan Windham-Bannister, CEO of MLSC commented, “the Center’s Accelerator Loan Program fills a critical gap in the life cycle of promising early-stage companies with a high potential for technology commercialization, rapid growth and access to private equity financing. Through this program the Massachusetts Life Sciences Center provides an endorsement of promising young companies, promotes their visibility and creates leverage for subsequent investors who can further help move these companies forward.”

Other efforts, like MassChallenge, are non-profit accelerators designed to provide extensive coaching and mentoring experiences along with free office space and an opportunity to compete for substantial cash and non-cash awards. A core benefit of such accelerators is the ability to quickly surround entrepreneurs with other highly motivated and impact focused teams. John Harthorne, CEO of MassChallenge noted, “aggregating this critical mass of vision, talent and drive leads to peer-to-peer learning and a wellspring of inspiration for entrepreneurs.”

Donna Brezinski, CEO of Little Sparrows, a medical device finalist in MassChallenge, credited the accelerator with “moving the Company forward much more rapidly than otherwise would have been possible. They connected us to industry experts, thought leaders and business mentors in both the life sciences and social impact spaces.” Matt Racki, Co-Founder of Gweepi Medical, a Health IT finalist, said “everyone in the MassChallenge community was dedicated to making the companies succeed.”
Other life science startups rely on organizations like University of Massachusetts Lowell’s Massachusetts Medical Device Development Center (M2D2) to help translate technology into prototypes. Still others, at even an earlier stage, utilize the coaching, “Platform Sessions,” investor conferences and events produced by the Massachusetts Technology Transfer Center (MTTC), which is charged with commercializing technology developed at Massachusetts universities and research institutions whether public or private.

Many life science entrepreneurs find that they immediately need to fill in a missing piece of their education around finding and transacting with angel and venture investors. The best entrepreneurs, however, leverage existing ecosystem resources to rapidly obtain education directly from investors. Samantha Hammar, Executive of The Capital Network, a Boston based non-profit, says of their day long Life Sci Fast Track Boot Camp “it is amazing to see 30-50 investors and mentors donate high value time to educate the next generation of entrepreneurs about the perils and thrills of building a high growth life science company.”

In addition to the not-for-profit organizations, there are for-profit but low cost incubators, co-working spaces and shared lab facilities. Each of these uses a different model to help new ventures execute their plans with maximum capital efficiency.

Entrepreneurs seeking high growth capital also should have leveraged the resources of their legal, accounting, banking and similar relationships. “Top tier firms can’t just deliver excellence in their core competencies. They also need to deliver their network, their business acumen, and value add services,” said Michelle Basil, Chair of the Life Sciences Practice Group at Nutter, McClennen & Fish LLP.

All life science companies face the extraordinary challenge of accelerating their research and development, investment and product commercialization processes. While entrepreneurs are the most self-reliant people on the planet, they would be well served to think of themselves as part of a larger environment and about the existing resources they can tap into in the surrounding life science ecosystem. Greater Boston’s most important competitive advantage is its incredible density and diversity of high value non-dilutive resources that facilitate the growth of life science companies.

Jeremy Halpern is a Partner and Director of Business Development – Emerging Companies Group for Nutter McClennen & Fish LLP. He will be participating at the upcoming Acceleration2013 Conference on December 9th.

Upstart Roundtable with Xavier Xicay

The Talent Wars- Today’s Toughest Startup Challenge

Sponsored by

Building a Fundable Team

It is an oft repeated truism that angels and venture capital firms invest in teams more than they invest in ideas and technologies. This roundtable will provide investors’ perspectives on this dilemma, along with a discussion of other team-related topics.

Understanding Angel and Venture Term Sheets

This limited seat luncheon brings some of Boston’s most experienced attorneys to provide 2 hours of deep instruction to entrepreneurs struggling to understand the complexity of high growth investments. Sample terms sheets will be provided and analyzed.

Working lunch programs are hosted by TCN’s professional service sponsors to provide tactical level information designed to accelerate the fundraising process.

Women helping women in entrepreneurship at MassChallenge

The Boston entrepreneurial community is home to some of the strongest and most successful women in entrepreneurship. Join the women of Golden Seeds and several local serial entrepreneurs for a discussion on sources of capital for your business. The discussion will be followed by small breakout sessions that focus on the challenges your company may be facing.

Building an Entire Investable Team

It is an oft repeated truism that angels and venture capital firms invest in teams more than they invest in ideas and technologies. The team, Board, and Advisory Board are extremely valuable. This roundtable will provide investors’ perspectives on this dilemma, along with a discussion of other team-related topics, Board and Advisory Board building strategies and management.

Regulatory 101 at M2D2

Many emerging companies make the mistake of putting all of their resources into immediate needs, and often neglect longterm regulatory strategy concerns when it comes to submissions and approvals. Don’t neglect the strategy piece in your planning! This lunch will provide a deep-dive foundation of how to develop a regulatory strategy.

Pitching the Plan: An Investor’s Perspective

Early stage ventures seeking investment need to know how to target, locate, approach and close with venture capitalists, angels and strategic investors. Through an interactive panel discussion with an entrepreneur and leading area entrepreneurs, attendees learn how to maximize their chances of identifying the right investors and securing the capital they need to grow their business. Attendees learn how to create an “Elevator Pitch” and what to include in their “Investment Deck”.

Structuring Founder Relationships: Stockholder Agreements and Choice of Entity

In this limited-seat Expert Lunch, learn how to tackle the structure of your founder relationships and equity agreements before they get in the way of your company’s ability to attract investment capital. Seating is limited to provide each entrepreneur time to get specific answers and guidance for his or her company. Lunch will be provided- come hungry for food and knowledge!

Copyright © 2012 The Capital Network, Inc. All Rights Reserved | Privacy Policy